To unravel the mechanisms and functions of RNA-mediated gene regulation.
We study the logics and biological impacts of gene silencing by RNA on the regulation of genes in development, physiology, and cancer.
Small non-coding RNAs such as microRNAs and siRNAs control gene expression by a diversity of mechanisms that affect messenger RNA transcription, translation, and stability. We integrate a full range of experimental strategies and models to understand how they function and how their defects lead to cancer.
The Duchaine lab is seeking graduate students, post doctoral fellows, and undergraduates to join us! Please contact us if you are interested!
Research in the Duchaine Lab is supported by
Duchaine Lab 