PhD Université de Montréal 2001
The common thread in the research interests of Dr. Duchaine is the functions of RNA and RNA-binding proteins in the control of genetic expression. Until 2001, Dr. Duchaine pursued his Ph.D. work at Université de Montréal in the lab of Luc Desgroseillers, where he used molecular biology to characterize the mammalian homologs of the RNA-binding protein Staufen. He moved on as a post-doctoral fellow, first in the lab of Nobel laureate Craig C. Mello at UMass Med. School (2001-2005), and later for a 1-year second post-doc at McGill University in the lab of Nahum Sonenberg (2005-2006). Since then, he leads an independent research program, now as an Associate Professor in the Goodman Cancer Research Centre (GCRC), and in the Department of Biochemistry at McGill. His current research revolves around the molecular aspects of RNA interference (RNAi), microRNAs, and their implications in cancer. Dr. Duchaine is cross-appointed in GCRC and Biochemistry and is also a member of the Experimental Medicine program. He teaches several courses, including undergraduate Biol314 (Biology of Cancer), Bioc454 (Nucleic Acids), Bioc/Anat212 (an entry-level biochemistry course), and graduate courses Bioc600D (Advances in Genetics and Genomics) and EXMD607 (Gene Expression).